Local flood risk assessment is important for both efficient flood management and climate change adaptation. The main aim of this thesis is to assess flood risk in the Oti River Basin (West Africa). The research methodology is articulated in four main steps namely (i) regional flood frequency analysis based on L-moments (ii) hydrological modelling for flood prediction, (iii) flood hazard mapping using flood inundation model and (iv) community-based flood risk assessment via a combination of flood hazard map, survey data on vulnerability, exposure and coping capacity. This thesis showed that flood risk in the Oti River Basin is relatively moderate and predominantly driven by high vulnerability and hazard. Both exposure and coping capacity are relatively low.